Reaktion #1441565

Reaktionsgleichung

3-(4-hydroxyphenyl)propionic acid

methionine methyl ester

→

title compound

Ausbeute 91.0%

2-[3-(4-hydroxyphenyl)propionylamino]-4-methylsulfanyl butyric acid methyl ester

Ausbeute 91.0%

Reaktionsbedingungen

Vorschrift

Following the same procedure of Example 4 except that 3-(4-hydroxyphenyl)propionic acid (1.0 g, 6.0 mmol) and methionine methyl ester (1.08 g, 6.6 mmol) were used, 1.7 g of the title compound was obtained. The compound was finally purified by silica gel column chromatography (column size: 25 mm×150 mm, silica gel 70-230 mesh, eluent: hexane/EtOAc (1/1)). The results of analyses of the compound are as follows:

Quelle