Reaktion #1408

Reaktionsgleichung

pivalaldehyde

3-aminopyrrolidine

→

3-(2,2-Dimethyl-propylidene-amino)-pyrrolidine

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONare added dropwise at 20° C. to 30° C.
2. 2
   Temperaturwhile cooling in a water bath
3. 3
   workup.DISTILLATIONis then distilled

Vorschrift

12.1 g (0.1 mol) of 71% strength pivalaldehyde, initially introduced into the reaction vessel and 8.6 g (0.1 mol) of 3-aminopyrrolidine are added dropwise at 20° C. to 30° C., while cooling in a water bath. The mixture is subsequently stirred at room temperature for 1 hour and is then distilled. Yield: 13.5 g (85% of theory), boiling point: 63° C.-65° C./10 to 12 mbar; content: 97%.

Quelle