Reaktion #1399

ord-f59502531b224cbdb38244051ab9c738

Reaktionsgleichung

Fc1ccc(Cc2ccc(F)cc2)cc1
4,4'-difluorodiphenylmethane
O
water
O=C(c1ccc(F)cc1)c1ccc(F)cc1
4,4'-difluorobenzophenone
Ausbeute 95.0%

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Sonstige20 g off-white solids, after toluene removal

Vorschrift

The procedure of Example 1 was used except that 20 g 4,4'-difluorodiphenylmethane, 30 g water, 31 g MnO2 and 50 g H2 SO4 were used. 20 g off-white solids, after toluene removal, afforded 95% pure 4,4'-difluorobenzophenone in a 90% yield.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05723676uspto-grants-1998_03