Reaktion #1376331

Reaktionsgleichung

methyl ketone

1,2,3,4-tetrahydro-1,4a,9b-trimethyl-1,4methanodibenzofuran-8-yl methyl ketone

chalcone

4-(ethoxycarbonyl)thiophenecarbaldehyde

→

ethyl 2-[(E)-3-(1,2,3,4-tetrahydro-1,4a,9b-trimethyl-1,4-methanodibenzofuran-8-yl)-3-oxo-1-propenyl]-4-thiophenecarboxylate

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto yield
2. 2
   Sonstigeafter recrystallization in ethyl acetate

Vorschrift

2.70 g (10 mmol) of the methyl ketone obtained in Example 3 were converted to chalcone in the presence of 1.7 g of 4-(ethoxycarbonyl)thiophenecarbaldehyde under the conditions described in Example 8 to yield, after recrystallization in ethyl acetate, 2.2 g (52%) of the expected compound, melting at 149°-151° C.

Quelle