Reaktion #1375839

Reaktionsgleichung

N-(4-Methylthiophenyl)-N-(n-butyl)alanine ethyl ester

Sodium hydroxide

→

N-(4-Methylthiophenyl)-N-(n-butyl)alanine sodium salt

Lösungsmittel

methanol

water

water

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe solvent was removed at reduced pressure
2. 2
   SonstigeThe resulting white solid was used without purification

Vorschrift

N-(4-Methylthiophenyl)-N-(n-butyl)alanine ethyl ester (3.0 g, 10.1 mmol) was dissolved in 50 mL methanol and 5 mL of water was added. Sodium hydroxide (0.41 g, 10.1 mmol) was dissolved in a minimum amount of water, and added to the aqueous methanol solution. The mixture was stirred 18 h at room temperature, and then the solvent was removed at reduced pressure. The resulting white solid was used without purification.

Quelle