Reaktion #1375013

Reaktionsgleichung

5-Nitro-2-(3-pyridinyl)benzothiazole

SnCl2

→

product

Ausbeute 80.0%

5-Amino-2-(3-pyridinyl)benzothiazole

Ausbeute 80.0%

Lösungsmittel

HCl

HCl

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe resulting mixture heated for 1 hour on a steam bath
2. 2
   TemperaturAfter cooling
3. 3
   Filtrationthe precipitate is filtered
4. 4
   Waschenwashed in cold HCl and neutralized in cold NaOh solution
5. 5
   FiltrationThe amine is filtered
6. 6
   Waschenwashed with H2O
7. 7
   Sonstigedried

Vorschrift

5-Nitro-2-(3-pyridinyl)benzothiazole 11.2 g, 0.044 mole, is dissolved in 45 cc of concentrated HCl. SnCl2, 35 g, in 45 cc of concentrated HCl is added, and the resulting mixture heated for 1 hour on a steam bath. After cooling, the precipitate is filtered, washed in cold HCl and neutralized in cold NaOh solution. The amine is filtered, washed with H2O and dried to yield 8.0 g of product m.p. 189°-196°.

Quelle