Reaktion #1372

Reaktionsgleichung

ethyl 2-methyl-3,4,6-trifluorobenzoylacetate

acetic anhydride

triethoxymethane

→

ethyl 2-(2-methyl-3,4,6-trifluorobenzoyl)-3-ethoxyacrylate

Ausbeute 90.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture is refluxed for 1 hour
2. 2
   EinengenAfter concentrating

Vorschrift

To ethyl 2-methyl-3,4,6-trifluorobenzoylacetate (3.2 g) are added acetic anhydride (3.0 g) and triethoxymethane (2.7 g) and the mixture is refluxed for 1 hour. After concentrating, ethyl 2-(2-methyl-3,4,6-trifluorobenzoyl)-3-ethoxyacrylate (3.5 g) is obtained.

Quelle