Reaktion #1365118

ord-89e3e405d3eb469cb54307c647dcde49

Reaktionsgleichung

COc1cc2c(cc1OC)-c1c(OC)c(OC)cc3c1[C@@H](C2)N(C)CC3
l-glaucine
[I-].[K+]
potassium iodide
→
COc1cc2c(cc1OC)-c1c(OC)c(OC)cc3c1[C@H](C2)N(C)CC3.I
glaucine hydroiodide

Edukte

—
l-glaucine hydroiodide
COc1cc2c(cc1OC)-c1c(OC)c(OC)cc3c1[C@@H](C2)N(C)CC3
l-glaucine
[I-].[K+]
potassium iodide

Reagenzien

Keine

Lösungsmittel

Cl
hydrochloric acid

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe resulting crystalline precipitate was recrystallized from a mixture of methyl alcohol and ether

Vorschrift

For making l-glaucine hydroiodide, a quantity of l-glaucine was dissolved in 2 n hydrochloric acid and the solution reacted with saturated potassium iodide solution. The resulting crystalline precipitate was recrystallized from a mixture of methyl alcohol and ether. This gave a crystalline, yellowish glaucine hydroiodide with a melting point of 238° C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04279914uspto-grants-1981_07