Reaktion #1365020

Reaktionsgleichung

N-[4-[3-(Trichloromethyl)phenoxy]-3-(trichloromethyl) phenyl]-N-(2,2-dimethoxyethyl)-N'-methylurea

hydrochloric acid

→

1-methyl-3[4-[3-(trichloromethyl)phenoxy]-3-(trichloromethyl)phenyl]-4-imidazolin-2-one

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigefitted with a mechanical stirrer
2. 2
   TemperaturThe mixture is refluxed for a period of about 30 minutes
3. 3
   Temperaturcooled
4. 4
   Extraktionextracted with ethyl acetate
5. 5
   WaschenThe extract is washed with dilute aqueous sodium bicarbonate, with two portions of water
6. 6
   Sonstigeis then dried
7. 7
   SonstigeThe ethyl acetate is removed
8. 8
   Temperaturby mild warming under reduced pressure

Vorschrift

N-[4-[3-(Trichloromethyl)phenoxy]-3-(trichloromethyl) phenyl]-N-(2,2-dimethoxyethyl)-N'-methylurea (0.02 mole), water (30 ml) and concentrated hydrochloric acid (3 ml) are charged into a glass reaction vessel fitted with a mechanical stirrer, thermometer and condenser. The mixture is refluxed for a period of about 30 minutes and then cooled and extracted with ethyl acetate. The extract is washed with dilute aqueous sodium bicarbonate, with two portions of water and is then dried. The ethyl acetate is removed by mild warming under reduced pressure to yield the desired product 1-methyl-3[4-[3-(trichloromethyl)phenoxy]-3-(trichloromethyl)phenyl]-4-imidazolin-2-one.

Quelle