Reaktion #1353162

Reaktionsgleichung

2,2-dibromo-1-methyl-1-phenylcyclopropane

acetic acid

→

2-bromo-1-methyl-1-phenylcyclopropane

Ausbeute 69.4%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe solvent was removed it vacuo
2. 2
   workup.ADDITIONTo the resulting residue hexanes and water were added
3. 3
   SonstigeThe resulting mixture was transferred to a separatory funnel
4. 4
   Sonstigethe phases were separated
5. 5
   TrocknenThe organic layer was dried over MgSO4
6. 6
   Filtrationfiltered
7. 7
   SonstigeThe solvent was removed from the filtrate in vacuo

Vorschrift

To a solution of 6.40 g (0.0221 mol) of 2,2-dibromo-1-methyl-1-phenylcyclopropane in 22 g of methanol was added 2.16 g (0.0360 mol) glacial acetic acid and 2.11 g (0.0323 mol) of zinc dust. After stirring at room temperature for 4 hours, the solvent was removed it vacuo. To the resulting residue hexanes and water were added. The resulting mixture was transferred to a separatory funnel and the phases were separated. The organic layer was dried over MgSO4 and filtered. The solvent was removed from the filtrate in vacuo to yield 3.24 g of 2-bromo-1-methyl-1-phenylcyclopropane as an oil which was used without further purification.

Quelle