Reaktion #1352268

ord-f1914aa01d5e45c8adb0d5d3870037a5

Reaktionsgleichung

O=C(N=C=S)c1ccco1
2-furoylisothiocyanate
CCOCc1nc2c(N)nc(C)c(C)c2n1CCC1CCNCC1
2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine
CCOCc1nc2c(N)nc(C)c(C)c2n1CCC1CCN(C(=S)NC(=O)c2ccco2)CC1
desired compound
CCOCc1nc2c(N)nc(C)c(C)c2n1CCC1CCN(C(=S)NC(=O)c2ccco2)CC1
N-[(4-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]ethyl}piperidin-1-yl)carbonothioyl]-2-furamide

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Using the method of Examples 54-65, 2-furoylisothiocyanate was reacted with 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 485.2357.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06545017B1uspto-grants-2003_04