Reaktion #1351
ord-69d79d7234c34dfc9b1df959b118c003
Reaktionsgleichung
ethanolamine
methyl acetoacetate
→
XXIII
Ausbeute 91.2%
3-(2-Hydroxyethylamino)-but-2-enoic acid methyl ester
Ausbeute 91.2%
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
To an ice-cooled sample of ethanolamine (6.1 g) was added methyl acetoacetate (11.6 g) dropwise. Compound (XXIII 14.5 g) was formed within 30 min (U.S. Pat. No. 1102800).