Reaktion #1349580

Reaktionsgleichung

7-Methyl-6-nitro-3H-benzoxazol-2-one

→

6-Amino-7-methyl-3H-benzoxazol-2-one

Ausbeute 98.0%

Lösungsmittel

Methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe mixture was filtered through Celite
2. 2
   Waschenwashed with MeOH and conc. in vacuo

Vorschrift

7-Methyl-6-nitro-3H-benzoxazol-2-one (0.895 g, 4.61 mmol) was hydrogenated in Methanol (30.0 mL) over 10% Palladium on Carbon (50% Wet) (0.135 g, 0.0634 mmol) under an atmosphere of Hydrogen (30 psi) for 2 h. The mixture was filtered through Celite, washed with MeOH and conc. in vacuo to afford 6-Amino-7-methyl-3H-benzoxazol-2-one (0.74 g, 98%).

Quelle