Reaktion #1285238

Reaktionsgleichung

4-(dodecylsulfonyl)butanoic acid

1,1'carbonyldiimidazole

magnesium chloride

ethyl potassium malonate

triethylamine

→

title compound

6-(dodecylsulfonyl)-3-oxo-hexanoic acid ethyl ester

Reaktionsbedingungen

Vorschrift

The title compound was prepared from 4-(dodecylsulfonyl)butanoic acid (H. Gilman, et al, J. Am Chem. Soc. 74, 4452 (1952)) (2.50 g, 0.07 mol), 1,1'carbonyldiimidazole (1.50 g, 0.09 mol), magnesium chloride (1.41 g, 0.014 mol), ethyl potassium malonate (2.12 g, 0.012 mol), and triethylamine (1.73 g, 0.017 mol) using the procedure described in Example 3, Step A.

Quelle