Reaktion #1285222
ord-261f53b7233a4b4ea50699ea81e617d0
Reaktionsgleichung
12-[(tetrahydro-2H-pyran-2-yl)oxy]-dodecanoic acid
magnesium chloride
ethyl potassium malonate
triethylamine
→
title compound
3-oxo-14-[(tetrahydro-2H-pyran-2-yl)oxy]-tetradecanoic acid ethyl ester
Edukte
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
The title compound was prepared from 12-[(tetrahydro-2H-pyran-2-yl)oxy]-dodecanoic acid (10.0 g, 0.033 mol), 1,11-carbonyldiimidazole (6.47 g, 0.039 mol), magnesium chloride (6.02 g, 0.063 mol), ethyl potassium malonate (9.06 g, 0.053 mol), and triethylamine (7.40 g, 0.073 mol) using the procedure described in Example 3, Step A.