Reaktion #1278657

Reaktionsgleichung

3-butyl-8-azabicyclo[3.2.1]octane

NaI

K2CO3

DMF

→

title compound ( 107LH74-c4 )

(R,S)-1-[3-(3-Butyl-8-azabicyclo[3.2.1]oct-8-yl)-2-methylpropyl]-3,4-dihydro-1H-quinolin-2-one

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigepurified

Vorschrift

Crude (R,S)-1-(3-chloro-2-methylpropyl)-3,4-dihydro-1H-quinolin-2-one (107LH63) (0.094 g), 3-butyl-8-azabicyclo[3.2.1]octane (0.025 g, 0.15 mmol), NaI (0.100 g, 0.67 mmol), and K2CO3 (0.075 g, 0.54 mmol) in DMF (1 mL) were reacted and purified according to GP20 to give the title compound (107LH74-c4) (0.025 g). HPLC-MS (ammonium acetate) [M+H]+=369.33.

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