Reaktion #1269835

Reaktionsgleichung

water

1,1-Dicyano-2-methoxy-2-(4-phenoxyphenyl)ethene

1,1-dicyano-2-methoxy-2-(4-phenoxyphenyl)ethene

hydrazine hydrate

→

3-amino-4-cyano-5-(4-phenoxyphenyl)pyrazole

Lösungsmittel

Ethanol

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturheated on the steambath for 1 hour
2. 2
   SonstigeThe precipitated solid is collected
3. 3
   Waschenwashed with ethanol:water (4:1)
4. 4
   Sonstigedried in air

Vorschrift

1,1-Dicyano-2-methoxy-2-(4-phenoxyphenyl)ethene (22.5 g) and 1,1-dicyano-2-methoxy-2-(4-phenoxyphenyl)ethene oil (15 g) are treated with a solution of hydrazine hydrate (18 mL) in ethanol (25 mL) and heated on the steambath for 1 hour. Ethanol (15 mL) is added followed by water (10 mL). The precipitated solid is collected and washed with ethanol:water (4:1) and then dried in air to give 3-amino-4-cyano-5-(4-phenoxyphenyl)pyrazole as a pale orange solid.

Quelle