Reaktion #1269823

Reaktionsgleichung

sodium 2-[3-(methacryloyloxy)-2,2-difluoro-n-pentanoyloxy]-1,1-difluoroethanesulfonate

water

triphenylsulfonium chloride

→

triphenylsulfonium 2-[3-(methacryloyloxy)-2,2-difluoro-n-pentanoyloxy]-1,1-difluoroethanesulfonate

Lösungsmittel

chloroform

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeInto a 100-mL reaction vessel
2. 2
   Sonstigesubjected to separation
3. 3
   WaschenThe thus-obtained organic phase was washed four times with 10 mL of water
4. 4
   Einengenconcentrated under a reduced pressure

Vorschrift

Into a 100-mL reaction vessel were added 2.82 g (purity: 24%, 1.74 mmol) of sodium 2-[3-(methacryloyloxy)-2,2-difluoro-n-pentanoyloxy]-1,1-difluoroethanesulfonate obtained in Preparation Example 4-1, 9 mL of water and 9 mL of chloroform. Further, 2.10 g (7.05 mmol) of triphenylsulfonium chloride was dropped into the reaction vessel at room temperature. The resulting solution was stirred for 2 hours at room temperature and subjected to separation. The thus-obtained organic phase was washed four times with 10 mL of water and concentrated under a reduced pressure. With this, 3.00 g of target triphenylsulfonium 2-[3-(methacryloyloxy)-2,2-difluoro-n-pentanoyloxy]-1,1-difluoroethanesulfonate was obtained as a colorless oily substance. The purity of the target product was 53%; and the yield of the target product was 100%.

Quelle