Reaktion #1251702

Reaktionsgleichung

hydrochloric acid

chlorocyclohexane

1,4-dichlorobenzene

aluminum chloride

→

1,4-dichloro-2-cyclohexylbenzene

Ausbeute 25.3%

Lösungsmittel

carbon disulfide

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.WAITAfter the stirring was continued for 3 hours at ambient temperature
2. 2
   workup.WAITto stand overnight at ambient temperature
3. 3
   workup.ADDITIONTo the reaction mixture was added dil
4. 4
   SonstigeThe organic layer was separated
5. 5
   Waschenwashed with water
6. 6
   Trocknendried over magnesium sulfate
7. 7
   Einengenconcentrated under reduced pressure
8. 8
   Sonstigeto stand at ambient temperature for a while
9. 9
   Sonstigeto give
10. 10
    Sonstigeprecipitates
11. 11
    SonstigeThe precipitates were removed by filtration
12. 12
    workup.DISTILLATIONThe filtrate was distilled under reduced pressure

Vorschrift

To a solution of 1,4-dichlorobenzene (294 g) in anhydrous carbon disulfide (400 ml) was added anhydrous aluminum chloride (16.0 g). To the mixture was added dropwise chlorocyclohexane (96 g) with stirring at ambient temperature during 3 hours. After the stirring was continued for 3 hours at ambient temperature, the reaction mixture was allowed to stand overnight at ambient temperature. To the reaction mixture was added dil.hydrochloric acid with stirring. The organic layer was separated, washed with water, dried over magnesium sulfate, concentrated under reduced pressure and allowed to stand at ambient temperature for a while to give precipitates. The precipitates were removed by filtration. The filtrate was distilled under reduced pressure to give 1,4-dichloro-2-cyclohexylbenzene (47.0 g).

Quelle