Reaktion #1247560

Reaktionsgleichung

triphenylphosphine

methyl 2-bromomethylbenzoate

diethyl ether

→

white powder

Ausbeute 81.0%

2-Methoxycarbonylbenzyltriphenylphosphonium bromide

Ausbeute 81.0%

Lösungsmittel

acetonitrile

acetonitrile

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe reaction mixture is refluxed
2. 2
   Temperaturcooled
3. 3
   workup.STIRRINGStirring
4. 4
   workup.WAITis continued for 2 hours
5. 5
   FiltrationThe solid is filtered off
6. 6
   Waschenwashed with acetone
7. 7
   SonstigeAfter drying

Vorschrift

74.2 g of triphenylphosphine (0.28 M) in 200 ml of acetonitrile are added to a solution of 74.5 g of methyl 2-bromomethylbenzoate (0.32 M) in 170 ml of acetonitrile in a 2000 ml reactor. The reaction mixture is refluxed with stirring for one hour and then cooled. 1000 ml of diethyl ether are then added slowly. Stirring is continued for 2 hours. A white precipitate forms. The solid is filtered off and washed with acetone. After drying, 112.6 g of a white powder are obtained (81% yield).

Quelle