Reaktion #1242170

Reaktionsgleichung

atropic acid, methyl ester

3-chlorophenylhydrazine hydrochloride

→

1-(3-chlorophenyl)-4-phenyl-3-pyrazolin-5-one

Ausbeute 79.9%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   WaschenThe reaction product mixture was washed up in the usual manner

Vorschrift

A mixture of 10.5 grams of the atropic acid, methyl ester, 9.1 grams 3-chlorophenylhydrazine hydrochloride, and 200 ml. methanol was refluxed overnight. The reaction product mixture was washed up in the usual manner to yield 11 grams of crude 1-(3-chlorophenyl)-4-phenyl-3-pyrazolin-5-one. A sample recrystallized from methanol had a melting point of about 211°-212° C.

Quelle