Reaktion #1204

Reaktionsgleichung

ethanolamine

ethanol

1,2-epoxyoctadecane

→

title compound

Ausbeute 74.6%

1-(2-hydroxyethylamino)-2-octadecanol

Ausbeute 74.6%

Lösungsmittel

Water

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeA 300-ml flask equipped with a stirrer and a dropping funnel
2. 2
   Sonstigereaction mixture, and white crystals
3. 3
   Sonstigeformed
4. 4
   Filtrationwere collected by filtration
5. 5
   Waschenwashed with water
6. 6
   Sonstigerecrystallized from methanol

Vorschrift

A 300-ml flask equipped with a stirrer and a dropping funnel was charged with 45.8 g (0.75 mol) of ethanolamine and 9 g of ethanol. While stirring the mixture at 80° C., 13.4 g (50 mmol) of 1,2-epoxyoctadecane were added dropwise over 2 hours. Water was added to the resultant reaction mixture, and white crystals formed were collected by filtration, washed with water and then recrystallized from methanol, thereby obtaining 12.3 g (yield: 74.6%) of the title compound (IIc-1).

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