Reaktion #1197294

Reaktionsgleichung

aniline

product

Diethyl 2-butyl-3-oxo-butanedioate

→

expected product

Ausbeute 45.2%

Diethyl 2-butyl-3-(phenylamino)-2-butenedioate

Ausbeute 45.2%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe reaction mixture was cooled
2. 2
   Sonstigechromatographed on silica eluant

Vorschrift

A mixture of 1 g of aniline and 2.65 g of the product of Step A and 150 mg of siliporite® NK10 was stirred for 3 days at 75° C. and the reaction mixture was cooled and chromatographed on silica eluant: hexane - ethyl acetate (9-1) to obtain 1.55 g of the expected product.

Quelle