Reaktion #1195912

Reaktionsgleichung

3-isobutyryl-2-propyl-1-(2-pyridylmethyl)indole-6-carboxamide

hydrogen chloride

→

3-isobutyryl-2-propyl-1-(2-pyridylmethyl)indole-6-carboxamide hydrochloride

Lösungsmittel

chloroform

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeAfter evaporation of solvent
2. 2
   Sonstigethe residue was crystallized from a mixture of ethanol and ethyl acetate

Vorschrift

To a solution of 3-isobutyryl-2-propyl-1-(2-pyridylmethyl)indole-6-carboxamide (80 mg) in chloroform (2 ml) was added 1M solution of hydrogen chloride in methanol (1 ml) at 25° C., and the mixture was stirred for 15 minutes. After evaporation of solvent, the residue was crystallized from a mixture of ethanol and ethyl acetate to give 3-isobutyryl-2-propyl-1-(2-pyridylmethyl)indole-6-carboxamide hydrochloride (80 mg) as colorless crystals.

Quelle