Reaktion #1194

Reaktionsgleichung

ethanolamine

10-(2-ethylhexyloxy)decyl glycidyl ether

→

title compound

Ausbeute 68.4%

1-(2-hydroxyethylamino)-3-[10-(2-ethylhexyloxy)decyloxy]-2-propanol

Ausbeute 68.4%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeA 200-ml two-necked flask equipped with a stirrer
2. 2
   Temperaturreflux tube
3. 3
   TemperaturWhile heating
4. 4
   workup.STIRRINGstirred further for 18 hours
5. 5
   Einengenit was concentrated under reduced pressure
6. 6
   Sonstigethe resultant residue was purified by column chromatography on silica gel

Vorschrift

A 200-ml two-necked flask equipped with a stirrer, reflux tube and dropping funnel was charged with 32.7 g (0.54 mol) of ethanolamine and 10.1 g of ethanol. While heating and stirring the mixture at 80° C., 1.76 g (5.14 mmol) of 10-(2-ethylhexyloxy)decyl glycidyl ether were added dropwise over 2 hours. After the resultant mixture was heated and stirred further for 18 hours, it was concentrated under reduced pressure, and the resultant residue was purified by column chromatography on silica gel, thereby obtaining 1.42 g (yield: 68%) of the title compound (Ia-14).

Quelle