Reaktion #1193857

Reaktionsgleichung

Hydrochloric acid ethyl acetate

2-(1-docosanoyl-2-piperidyl)ethyl 4-methyltetrahydro-1(2H)-pyrazinecarboxylate

→

compound

2-(1-Docosanoyl-2-piperidyl)ethyl 4-methyltetrahydro- 1 (2H)-pyrazinecarboxylate hydrochloride

Lösungsmittel

ethyl acetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwhile being cooled with ice
2. 2
   EinengenAfter the reaction mixture was concentrated
3. 3
   Sonstigethe residue was recrystallized with ethyl acetate

Vorschrift

4N Hydrochloric acid/ethyl acetate solution (1.46 ml) was added to a solution of 2-(1-docosanoyl-2-piperidyl)ethyl 4-methyltetrahydro-1(2H)-pyrazinecarboxylate (2.800 g) in ethyl acetate (28 ml), while being cooled with ice. The mixture was stirred for 30 minutes. After the reaction mixture was concentrated, the residue was recrystallized with ethyl acetate, thereby yielding the entitled compound (2.590 g) as white solid.

Quelle