Reaktion #1185921

Reaktionsgleichung

2-[4-(6-Benzyloxyhexanoylamino)-phenoxy]-propionic acid methyl ester

→

2-[4-(6-Hydroxyhexanoylamino)-phenoxy]-propionic acid methyl ester

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeCatalyst was removed by filtration and methanol
2. 2
   workup.DISTILLATIONdistilled off

Vorschrift

2-[4-(6-Benzyloxyhexanoylamino)-phenoxy]-propionic acid methyl ester 59 (15 g, 37.59 mmol) was dissolved in methanol (150 ml) in a pressure vessel. Palladium on carbon (50% wet, 5%, 15 g) was added and the mixture stirred under hydrogen atmosphere (4 kg) for 16 hrs. Catalyst was removed by filtration and methanol distilled off.

Quelle