Reaktion #1184

Reaktionsgleichung

1-fluoro-2-methyl-4-nitrobenzene

hydrazine hydrate

hydrazine hydrate

→

expected product

1-Hydrazino-2-methyl-4-nitrobenzene hydrofluoride

Lösungsmittel

2-propanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturis heated
2. 2
   Temperaturto reflux for 2 hours
3. 3
   Temperaturrefluxing
4. 4
   workup.WAITthe mixture is left overnight
5. 5
   SonstigeThe precipitate formed

Vorschrift

A mixture of 4.6 g of 1-fluoro-2-methyl-4-nitrobenzene and 3 ml of hydrazine hydrate in 45 ml of 2-propanol is heated to reflux for 2 hours. 3 ml of hydrazine hydrate are added, refluxing is continued for 2 hours and the mixture is left overnight with stirring at RT. The precipitate formed is drained. 3.53 g of the expected product are obtained, m.p.=182° C.

Quelle