Reaktion #1178397

Reaktionsgleichung

p-methoxybenzophenone

→

1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene

Ausbeute 91.0%

Lösungsmittel

THF

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed for 20 h
2. 2
   Filtrationfiltered
3. 3
   SonstigeThe filtrates were evaporated
4. 4
   Sonstigethe crude product was purified by a silica gel column

Vorschrift

A suspension of p-methoxybenzophenone (1.06 g, 5.0 mmol), 1.34 equiv of TiCl3/AlCl3 (5.81 g, 6.7 mmol), and 25 equiv of Zn dust (8.01 g, 122.0 mmol) in 100 ml of dry THF was refluxed for 20 h. The reaction mixture was cooled to room temperature and filtered. The filtrates were evaporated and the crude product was purified by a silica gel column using hexane as eluent. 1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene (TPE-OMe) was isolated in 91% yield.

Quelle