Reaktion #1174332

Reaktionsgleichung

5-acetyl-2,2-dimethyl-1,3-dioxane-4,6-dione

4-(1-ethoxyethoxy)cinnamyl alcohol

tetrahydrofuran

→

4-[(1-ethoxy)ethoxy]cinnamyl acetoacetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwere refluxed for 6 hours
2. 2
   Sonstigethe solvent was removed by evaporation
3. 3
   Sonstigethe residue thus obtained
4. 4
   Sonstigewas purified by means of a silica gel column chromatography (eluent: ethyl acetate:n-hexane=1:4)

Vorschrift

18.6 Grams of 5-acetyl-2,2-dimethyl-1,3-dioxane-4,6-dione and 50 ml tetrahydrofuran solution containing 22.2 g of 4-(1-ethoxyethoxy)cinnamyl alcohol were refluxed for 6 hours. After the reaction was completed, the solvent was removed by evaporation, and the residue thus obtained was purified by means of a silica gel column chromatography (eluent: ethyl acetate:n-hexane=1:4) to yield 5.8 g of 4-[(1-ethoxy)ethoxy]cinnamyl acetoacetate as in the form of an oily substance.

Quelle