Reaktion #1172435

ord-25cb7accfe7e4d2b873f24e05316be95

Reaktionsgleichung

Cn1c(N2CCN(CCCOc3ccc([N+](=O)[O-])cc3)CC2)cc(=O)n(C)c1=O
1,3-dimethyl-6-{4-[3-(4-nitrophenoxy)propyl]piperazin-1-yl}-2,4(1H,3H)-pyrimidinedione
CO.Cl
hydrochloric acid methanol
→
Cl.Cn1c(N2CCN(CCCOc3ccc([N+](=O)[O-])cc3)CC2)cc(=O)n(C)c1=O
compound 35
Cl.Cn1c(N2CCN(CCCOc3ccc([N+](=O)[O-])cc3)CC2)cc(=O)n(C)c1=O
1,3-dimethyl-6-{4-[3-(4-nitrophenoxy)propyl]piperazin-1-yl}-2,4(1H,3H)-pyrimidinedione hydrochloride

Edukte

Cn1c(N2CCN(CCCOc3ccc([N+](=O)[O-])cc3)CC2)cc(=O)n(C)c1=O
1,3-dimethyl-6-{4-[3-(4-nitrophenoxy)propyl]piperazin-1-yl}-2,4(1H,3H)-pyrimidinedione
CO.Cl
hydrochloric acid methanol

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Furthermore, the thus obtained 1,3-dimethyl-6-{4-[3-(4-nitrophenoxy)propyl]piperazin-1-yl}-2,4(1H,3H)-pyrimidinedione was treated with a hydrochloric acid/methanol solution in a usual manner to obtain 1,3-dimethyl-6-{4-[3-(4-nitrophenoxy)propyl]piperazin-1-yl}-2,4(1H,3H)-pyrimidinedione hydrochloride (compound 35).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05008267uspto-grants-1991_04