Reaktion #1166463

Reaktionsgleichung

3-methoxy-4-benzyloxy-7-acetoxy-2H-1-benzopyran -2-one

sodium methoxide

→

title compound

Ausbeute 81.1%

3-methoxy-7-hydroxy-4-benzyloxy-2H-1-benzopyran-2-one

Ausbeute 81.1%

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONThen 2.31 g of Amberlyst-15 (Trademark: Organo corp.) was added
2. 2
   workup.STIRRINGthe mixture was stirred at room temperature for 1 hour
3. 3
   Einengenthe filtrate was concentrated under reduced pressure
4. 4
   SonstigeThe precipitate was obtained during concentration
5. 5
   Filtrationfiltered

Vorschrift

To a mixture of 3.64 g of 3-methoxy-4-benzyloxy-7-acetoxy-2H-1-benzopyran -2-one (10.7 mmol) in 50 ml of methanol was added 0.58 g of sodium methoxide (10.7 mmol) and the mixture was stirred at room temperature for 1 hour. Then 2.31 g of Amberlyst-15 (Trademark: Organo corp.) was added, and the mixture was stirred at room temperature for 1 hour. Amberlyst-15 was filterd off, the filtrate was concentrated under reduced pressure. The precipitate was obtained during concentration and filtered to give 2.59 g of the title compound. (yield=77%)

Quelle