Reaktion #11643

Reaktionsgleichung

4-(1-methylpiperidin-3-ylmethoxy)-phenylamine

6-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one

→

compound

Ausbeute 55.0%

6-Fluoro-3-{[4-(1-methyl-piperidin-3-ylmethoxy)-phenylamino]-methylene}-1,3-dihydro-indol-2-one

Ausbeute 55.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeare reacted

Vorschrift

In a manner similar to that described in Example 231, 4-(1-methylpiperidin-3-ylmethoxy)-phenylamine (590 mg, 1.2 equiv.) and 6-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one (400 mg, 2.23 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (466 mg, 55%).

Quelle