Reaktion #11631

Reaktionsgleichung

4-(3-Diethylamino-propoxy)-3-fluoro-phenylamine

4-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one

→

compound

Ausbeute 67.4%

3-{[4-(3-Diethylamino-propoxy)-3-fluoro-phenylamino]-methylene}-4-fluoro-1,3-dihydro-indol-2-one

Ausbeute 67.4%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeare reacted

Vorschrift

In a manner similar to that described in Example 231, 4-(3-Diethylamino-propoxy)-3-fluoro-phenylamine (720 mg, 1.5 equiv.) and 4-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one (358 mg, 2.00 mmol) are reacted to give the named compound as a yellow solid (541 mg, 67%).

Quelle