Reaktion #11613

Reaktionsgleichung

4-(4-piperidin-1-yl-butoxy)-phenylamine

6-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one

→

compound

Ausbeute 73.0%

6-Fluoro-3-{[4-(4-piperidin-1-yl-butoxy)-phenylamino]-methylene}-1,3-dihydro-indol-2-one

Ausbeute 73.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeare reacted

Vorschrift

In a manner similar to that described in Example 231, 4-(4-piperidin-1-yl-butoxy)-phenylamine (400 mg, 1.1 equiv.) and 6-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one (263 mg, 1.47 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (435 mg, 73%).

Quelle