Reaktion #11610

Reaktionsgleichung

4-(3-piperidin-1-yl-propoxy)-phenylamine

5-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one

→

compound

Ausbeute 66.1%

5-Fluoro-3-{[4-(3-piperidin-1-yl-propoxy)-phenylamlino]-methylene}-1,3-dihydro-indol-2-one

Ausbeute 66.1%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeare reacted

Vorschrift

In a manner similar to that described in Example 231, 4-(3-piperidin-1-yl-propoxy)-phenylamine (0.57 g, 1.3 equiv.) and 5-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one (0.363 g, 2 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (379 mg, 47%).

Quelle