Reaktion #1157993

ord-1a06e565f8c34bd287fc90bb011992ce

Reaktionsgleichung

CN(C(=O)Cl)c1ccccc1
N-methyl-N-phenylcarbamoyl chloride
CCOCc1nc2c(N)nc(C)c(C)c2n1CCC1CCNCC1
2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine
CCOCc1nc2c(N)nc(C)c(C)c2n1CCC1CCN(C(=O)N(C)c2ccccc2)CC1
desired compound
CCOCc1nc2c(N)nc(C)c(C)c2n1CCC1CCN(C(=O)N(C)c2ccccc2)CC1
4-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]ethyl}-N-methyl-N-phenylpiperidine-1-carboxamide

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Using the method of Examples 54-65, N-methyl-N-phenylcarbamoyl chloride was reacted with 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 465.3006.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06903113B2uspto-grants-2005_06