Reaktion #1152637

ord-7b6ffddd13a84b849d2635e6a7dcf5cb

Reaktionsgleichung

Cc1cc(C(C)(C)C)ccc1SCCCCOc1ccc2c(c1)CCC(=O)N2
6-[4-(2-methyl-4-tert. butylphenyl-mercapto)-butoxy]-3,4-dihydro-carbostyril
OO
hydrogen peroxide
→
Cc1cc(C(C)(C)C)ccc1S(=O)CCCCOc1ccc2c(c1)CCC(=O)N2
6-[4-(2-Methyl-4-tert. butylphenyl-sulfinyl)-butoxy]-3,4-dihydro-carbostyril

Edukte

Cc1cc(C(C)(C)C)ccc1SCCCCOc1ccc2c(c1)CCC(=O)N2
6-[4-(2-methyl-4-tert. butylphenyl-mercapto)-butoxy]-3,4-dihydro-carbostyril
OO
hydrogen peroxide

Reagenzien

Keine

Lösungsmittel

CO.ClCCCl
ethylene chloride methanol

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Prepared analogous to Example 123 from 6-[4-(2-methyl-4-tert. butylphenyl-mercapto)-butoxy]-3,4-dihydro-carbostyril and hydrogen peroxide. Resinous substance. Rf -value: 0.54 (silica gel fluorescent plate; eluant: ethylene chloride/methanol=95/5).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04329347uspto-grants-1982_05