Reaktion #1150356

ord-7d81f4d30f9e4ab8a1224dcb5cbed38b

Reaktionsgleichung

CN(Cc1ccncc1)C(=O)c1cc2nccc(Cl)c2s1
7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid methyl-pyridin-4-ylmethyl-amide
Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
→
Cc1cc2cc(Nc3ccnc4cc(C(=O)N(C)Cc5ccncc5)sc34)ccc2[nH]1
title compound
Cc1cc2cc(Nc3ccnc4cc(C(=O)N(C)Cc5ccncc5)sc34)ccc2[nH]1
7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carboxylic acid methyl-pyridin-4-ylmethyl-amide

Edukte

CN(Cc1ccncc1)C(=O)c1cc2nccc(Cl)c2s1
7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid methyl-pyridin-4-ylmethyl-amide
Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid methyl-pyridin-4-ylmethyl-amide and 2-methyl-1H-indol-5-ylamine by a method analogous to Example 1C. MS: 428 (MH+); HPLC Rf: 4.26 min; HPLC purity: 93%.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06964961B2uspto-grants-2005_11