Reaktion #1150337

ord-e9284e8b93f8495ea807a11a75d5d711

Reaktionsgleichung

Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
O=C(NCCc1ccccn1)c1cc2nccc(Cl)c2s1
7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid (2-pyridin-2-yl-ethyl)-amide
→
Cc1cc2cc(Nc3ccnc4cc(C(=O)NCCc5ccccn5)sc34)ccc2[nH]1
title compound
Cc1cc2cc(Nc3ccnc4cc(C(=O)NCCc5ccccn5)sc34)ccc2[nH]1
7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carboxylic acid (2-pyridin-2-yl-ethyl)-amide

Edukte

Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
O=C(NCCc1ccccn1)c1cc2nccc(Cl)c2s1
7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid (2-pyridin-2-yl-ethyl)-amide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid (2-pyridin-2-yl-ethyl)-amide by a procedure analogous to Example 1C. MS: 428 (MH+), HPLC Rf: 4.33 min; HPLC purity 99%.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06964961B2uspto-grants-2005_11