Reaktion #1150335

ord-2699433365da41ed92b418a764a11a7b

Reaktionsgleichung

Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
O=C(NCc1ccncc1)c1cc2nccc(Cl)c2s1
7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid (pyridin-4-ylmethyl)-amide
→
Cc1cc2cc(Nc3ccnc4cc(C(=O)NCc5ccncc5)sc34)ccc2[nH]1
title compound
Cc1cc2cc(Nc3ccnc4cc(C(=O)NCc5ccncc5)sc34)ccc2[nH]1
7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carboxylic acid (pyridin-4-ylmethyl)-amide

Edukte

Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
O=C(NCc1ccncc1)c1cc2nccc(Cl)c2s1
7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid (pyridin-4-ylmethyl)-amide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid (pyridin-4-ylmethyl)-amide by a procedure analogous to Example 1C. MS: 414 (MH+), HPLC Rf: 3.97 min.; HPLC purity 94%.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06964961B2uspto-grants-2005_11