Reaktion #1150327

ord-20143256c2a2496f9b44c9c1b5623847

Reaktionsgleichung

Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
O=C(NCc1ccccn1)c1cc2nccc(Cl)c2s1
7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid (pyridin-2-ylmethyl)-amide
→
Cc1cc2cc(Nc3ccnc4cc(C(=O)NCc5ccccn5)sc34)ccc2[nH]1
title compound
Cc1cc2cc(Nc3ccnc4cc(C(=O)NCc5ccccn5)sc34)ccc2[nH]1
7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carboxylic acid (pyridin-2-ylmethyl)-amide

Edukte

Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
O=C(NCc1ccccn1)c1cc2nccc(Cl)c2s1
7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid (pyridin-2-ylmethyl)-amide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid (pyridin-2-ylmethyl)-amide by a procedure analogous to Example 1C. MS: 414 (MH+); HPLC Rf: 4.34 min.; HPLC purity: 97%.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06964961B2uspto-grants-2005_11