Reaktion #1150325

ord-9c773520bac547d2b1afbbd05d39f226

Reaktionsgleichung

Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
CNC(=O)c1cc2nccc(Cl)c2s1
7-Chloro-thieno[3,2-b]pyridine-2-carboxylic acid methylamide
→
CNC(=O)c1cc2nccc(Nc3ccc4[nH]c(C)cc4c3)c2s1
title compound
CNC(=O)c1cc2nccc(Nc3ccc4[nH]c(C)cc4c3)c2s1
7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carboxylic acid methylamide

Edukte

Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
CNC(=O)c1cc2nccc(Cl)c2s1
7-Chloro-thieno[3,2-b]pyridine-2-carboxylic acid methylamide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-Chloro-thieno[3,2-b]pyridine-2-carboxylic acid methylamide by a procedure analogous to Example 1C. MS: 337 (MH+); HPLC Rf: 3.86 min.; HPLC purity: 98%.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06964961B2uspto-grants-2005_11