Reaktion #1150321

ord-49fee27922634c6e93e6cc442a0ffd34

Reaktionsgleichung

Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
CN(C)C(=O)c1cc2nccc(Cl)c2s1
7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid dimethylamide
→
Cc1cc2cc(Nc3ccnc4cc(C(=O)N(C)C)sc34)ccc2[nH]1
title compound
Cc1cc2cc(Nc3ccnc4cc(C(=O)N(C)C)sc34)ccc2[nH]1
7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carboxylic acid dimethylamide

Edukte

Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
CN(C)C(=O)c1cc2nccc(Cl)c2s1
7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid dimethylamide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid dimethylamide by a procedure analogous to Example 1C. MS: 351 (MH+); HPLC Rf: 3.87 min.; HPLC purity: 94%.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06964961B2uspto-grants-2005_11