Reaktion #1150317

ord-ae4289169e004b2282f5bea7c37a81c9

Reaktionsgleichung

Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
CCNC(=O)c1cc2nccc(Cl)c2s1
7-Chloro-thieno[3,2-b]pyridine-2-carboxylic acid ethylamide
→
CCNC(=O)c1cc2nccc(Nc3ccc4[nH]c(C)cc4c3)c2s1
title compound
CCNC(=O)c1cc2nccc(Nc3ccc4[nH]c(C)cc4c3)c2s1
7-(2-Methyl-1H-indol-5-ylamino)-thieno[3,2-b]pyridine-2-carboxylic acid ethylamide

Edukte

Cc1cc2cc(N)ccc2[nH]1
2-methyl-1H-indol-5-ylamine
CCNC(=O)c1cc2nccc(Cl)c2s1
7-Chloro-thieno[3,2-b]pyridine-2-carboxylic acid ethylamide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 2-methyl-1H-indol-5-ylamine and 7-Chloro-thieno[3,2-b]pyridine-2-carboxylic acid ethylamide by a procedure analogous to Example 1C. MS: 351 (MH+); HPLC Rf: 4.33 min; HPLC purity: 98%.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06964961B2uspto-grants-2005_11