Reaktion #1147874

ord-8b43fe5e119d40f19f562315f329b9ad

Reaktionsgleichung

CN(C)S(=O)(=O)Cl
dimethylsulfamoyl chloride
CCOCc1nc2c(N)nc(C)c(C)c2n1CCC1CCNCC1
2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine
→
CCOCc1nc2c(N)nc(C)c(C)c2n1CCC1CCN(S(=O)(=O)N(C)C)CC1
desired product
CCOCc1nc2c(N)nc(C)c(C)c2n1CCC1CCN(S(=O)(=O)N(C)C)CC1
4-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]ethyl}-N,N-dimethylpiperidine-1-sulfonamide

Edukte

CN(C)S(=O)(=O)Cl
dimethylsulfamoyl chloride
CCOCc1nc2c(N)nc(C)c(C)c2n1CCC1CCNCC1
2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Using the method of Examples 49-56, dimethylsulfamoyl chloride was reacted with 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired product. The observed accurate mass was 439.2510.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06525064B1uspto-grants-2003_02