Reaktion #1146220

ord-089c3ffd0a8a4c4a845a01da2fcca141

Reaktionsgleichung

C=CCON(C(C)(C)C)C(C)(C)C(=O)NC(C)(C)C
compound ( 204 )
C=CCON(C(C)(C)C)C(C)(C)C(=O)NC(C)(C)C
N-allyloxy-tert-butyl-(dimethyl-tert-butylaminocarbonyl-methyl)-amine
CC(C)(C)NC(=O)C(C)(C)N(O)C(C)(C)C
tert-butyl-(dimethyl-tert-butylaminocarbonyl-methyl)-hydroxylamine
C#CCBr
propargylbromide
→
C#CCON(C(C)(C)C)C(C)(C)C(=O)NC(C)(C)C
N-propargyloxy-tert-butyl-(dimethyl-tert-butylaminocarbonyl-methyl)-amine
Ausbeute 78.0%

Edukte

C=CCON(C(C)(C)C)C(C)(C)C(=O)NC(C)(C)C
compound ( 204 )
C=CCON(C(C)(C)C)C(C)(C)C(=O)NC(C)(C)C
N-allyloxy-tert-butyl-(dimethyl-tert-butylaminocarbonyl-methyl)-amine
CC(C)(C)NC(=O)C(C)(C)N(O)C(C)(C)C
tert-butyl-(dimethyl-tert-butylaminocarbonyl-methyl)-hydroxylamine
C#CCBr
propargylbromide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The compound is prepared in analogy to compound (204) from tert-butyl-(dimethyl-tert-butylaminocarbonyl-methyl)-hydroxylamine and propargylbromide in 78% yield as colorless oil.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06518326B1uspto-grants-2003_02