Reaktion #11396

Reaktionsgleichung

5-amino-1-(2′,4′-difluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid

3-aminopyrrolidine

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titled product

Ausbeute 71.0%

5-Amino-1-(2′,4′-difluorophenyl)-6,8-difluoro-1,4-dihydro-7-(3-aminopyrrolidine -1-yl)-4-oxo-quinoline-3-carboxylic acid

Ausbeute 71.0%

Reaktionsbedingungen

Vorschrift

The condensation of 5-amino-1-(2′,4′-difluorophenyl)-6,7,8-trifluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid with 3-aminopyrrolidine was carried out in a similar manner as described in example 1, gave the titled product. Yield 71%, m.p 268° C. (d), C20H16F4N4O3, m/z 437 (M+1).

Quelle