Reaktion #11394

Reaktionsgleichung

5-amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid

3-aminomethyl-4-hydroxy-piperidine

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titled product

Ausbeute 52.8%

5-Amino-1-(cyclopropyl)-6,8-difluoro-1,4-dihydro-7-(3′-aminomethyl-4′-hydroxy-piperidin-1-yl)-4-oxo-quinoline-3-carboxylic acid

Ausbeute 52.8%

Reaktionsbedingungen

Vorschrift

The condensation of 5-amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid with 3-aminomethyl-4-hydroxy-piperidine was carried out in a similar manner as described in example 1, gave the titled product. Yield 52.8%, m.p 202–04° C., C19H22F2N4O4, m/z 409 (M+1).

Quelle