Reaktion #11392

Reaktionsgleichung

5-amino-1-cyclopropyl-6,7-difluoro-8-methoxy -1,4-dihydro-4-oxo-quinoline-3-carboxylic acid

4-amino-3-methylpiperidine

→

titled product

Ausbeute 50.0%

5-Amino-1-cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-7-(4′-amino-3′-methylpiperidin-1-yl)-4-oxo-quinoline-3-carboxylic acid

Ausbeute 50.0%

Reaktionsbedingungen

Vorschrift

The condensation of 5-amino-1-cyclopropyl-6,7-difluoro-8-methoxy -1,4-dihydro-4-oxo-quinoline-3-carboxylic acid with 4-amino-3-methylpiperidine was carried out in a similar manner as described in example 1, gave the titled product. Yield 50%, m.p 260–62° C., C20H25FN4O4, m/z 405 (M+1).

Quelle